Howard Mount
PhD
Research Synopsis
Keywords: Alzheimer’s disease, Animal Models, ataxia telangiectasia, biogenic amines, Brain, CNS, cortex, emotion, energy homeostasis, fear, hippocampus, learning, memory, motor behaviour, neuropharmacology, pain, Parkinson’s disease, signal transduction, stress.
METHODS USED
Cell and tissue cultures: primary neuronal culture (cerebellar Purkinje cells, granule cells, cortical neurons, ventral mesencephalic neurons) Procedures: Behavioural tests, Elisa, HPLC, Immunocytochemistry, Western blot.
EQUIPMENT USED
Analytical balances, benchtop centrifuge, blotting apparatus, culture hood, culture incubators, dissecting microscope, fluorescence microscope, gel apparatus, HPLC (Dionex HPLC-UV &HPLC-EC systems), infusion apparatus, microwave oven (Muromachi Brain Fixation System: 10; KWatt microwave with mouse applicator), plate reader, real-time/Thermocycler, setups for eletropherosis, stirrer/hot plate, water baths.
PRESENT TRAINEES
Keith Ho
PRESENT COLLABORATIONS
Richard Bazinet, Dept. Nutrition & Food Science, Univ Toronto
Margaret Fahnestock, McMaster Univ, Hamilton, Canada
Kevin Kain, Dept. Medicine, Univ Toronto
Jean Mariani, Inst. Pierre et Marie Curie, Paris, France
JoAnne McLaurin , Dept. Laboratory Medicine & Pathobiology, Univ Toronto
Janice Robertson, Dept. Laboratory Medicine & Pathobiology, Univ Toronto
Brian Robinson, Dept. Biochemistry, Univ Toronto
Gerold Schmitt-Ulms, Dept. Laboratory Medicine & Pathobiology, Univ Toronto
Lena Serghides, McGlaughlin-Rotman Centre for Global Health, Univ Toronto
Anurag Tandon, Dept. Medicine, Univ Toronto
Committee member of national/international scientific organization
Associate Editor, Journal of Alzheimer’s Disease Research