Dr. Daniel Minor: "Electrosome assembly: a first structural view of ion channel biogenesis"
~ Eligible for PSL1000H/PSL2000H/PSL4000Y Course Seminar Attendance ~
Speaker: Dr. Daniel Minor
Professor
Cardiovascular Research Institute
Departments of Biochemistry & Biophysics,
and Cellular & Molecular Pharmacology
California Institute for Quantitative Biomedical Research
Kavli Institute for Fundamental Neuroscience
University of California, San Francisco
Biography:
I have a broad background in ion channel structural biology and functional characterization, with specific expertise and prior accomplishments directly relevant to this application. My interest in the physical chemistry of biological phenomena began with my undergraduate study in biophysics and biochemistry at the University of Pennsylvania. As a graduate student in the Department of Chemistry at MIT with Prof. Peter S. Kim, I focused on understanding the basic principles of protein folding and molecular interactions. While at MIT, I developed a keen interest in the proteins involved in electrical signaling. To pursue this interest, I was a postdoctoral fellow with Dr. Nigel Unwin at the LMB Cambridge and with Prof. Lily Y. Jan at UCSF where I applied my structural biology background to questions regarding ion channel structure and regulation. As a PI, I have focused my laboratory’s efforts on structural and mechanistic understanding of ion channels. My lab is pursuing a research program that combines structural biology, functional studies of ion channels, and development of novel means to control channel function, and studies of toxin resistance. Our central goals are to obtain a structural understanding of ion channel action and regulation and to leverage this knowledge to gain control of channel function. We have had a long-standing effort on CaVs and K2Ps that has made seminal contributions to our understanding of how they function and in the development of new channel modulators. I am a Professor of Biochemistry and Biophysics and Cellular and Molecular Pharmacology, an Investigator in the Cardiovascular Research Institute at UCSF, and a Faculty Scientist at LBNL.
Websites:
https://cvri.ucsf.edu/people/daniel-minor-phd
https://profiles.ucsf.edu/daniel.minor
https://scvrb-core.ucsf.edu/~dminor/
Location: MSB 2170 (in-person only)