JCV3062H - Advanced Topics in Cardiovascular Sciences: Heart Function

Course Coordinator: 

R. Bentley

Description:

This course is one of a set of seven advanced seminar half-credit courses dealing with current areas in the cardiovascular system. Specifically, JCV3062H covers all aspects of heart function from ultra structure and gene regulation to whole organ and response to various environmental and disease states.

Areas that may be covered include:

• Mechanisms of right heart failure

• Endoplasmic reticulum: ultra structure and protein composition of calcium storage/release sites in cardiac muscle

• Sarcoplasmic reticulum, calcium and its regulation in cardiac function 

• Phospholamban in the regulation of cardiac kinetics 

• Anemia as a model for cardiovascular adaptation and oxygen homeostasis

• Genes associated with cardiovascular systems and multifactorial disease 

• Integrative approach to the regulation of cardiac function and blood pressure

• Cancer and cardiometabolic function

• Cardiac remodeling and exercise

• Cardiac function in adverse environments 

• Mechanical heart assist

For the complete course outline, visit http://www.cscp.utoronto.ca

Prerequisite:

None.

Evaluation:

40%   written essay: Dec 4
30%   student oral presentation: Dec 1
10%   student seminar: Sept 29
10%   essay outline: Oct 16
10%   participation: Throughout
Notes: Deadlines may be adjusted as the course syllabus is finalized
 

Remarks:

Enrolment restrictions: Graduate students or research fellows interested in heart research. Preference will be given to students enrolled in the Cardiovascular Sciences Collaborative Program.