Philippe Monnier

Our research integrates neuroscience, vascular biology, and regenerative medicine, driving new insights into the mechanisms underlying brain development, neurological disease, and tissue repair. In particular, our work on the Repulsive Guidance Molecule (RGM) family of proteins and their receptors has shown that these proteins play key roles in neural development, neuronal survival, and regeneration. Our studies have uncovered important mechanisms that limit repair in the injured central nervous system, which has led to the development of innovative strategies to promote neural regeneration following conditions such as spinal cord injury and stroke. More recently, our work has expanded to the study of angiogenesis and neurovascular biology, exploring how blood vessels and neural cells interact during development, disease, and tissue repair. This research aims to advance our understanding of how vascular and neural networks are coordinated and how they can be harnessed to support regeneration and recovery after brain and ocular injuries.

We are looking for students who would be interested in investigating the role of blood borne ATP in CNS development and CNS homeostasis.

Faculty Appointments

Professor, Department of Ophthalmology
Senior Scientist, Krembil Brain Institute