Overview: This course integrates the newest findings and experimental approaches from cellular and molecular biology into metabolic function at the tissue, organ and whole-body level.
Learning Objectives:
To integrate the fundamentals of fuel and energy metabolism and its endocrine regulation into a whole-body perspective
To grasp the current concepts in obesity and diabetes research
To start formulating hypotheses and designing experimental approaches to address specific questions in the area of metabolism.
To learn how to read and write a scientific paper.
Topics Covered:
Glucose & glycogen metabolism
Insulin action & resistance
Hormone receptor and signaling pathway
Lipid, ketone and protein metabolism
Lipoprotein and cholesterol metabolism
Insulin secretion
Obesity and feeding regulation
Type 1 and Type 2 diabetes
Complications of diabetes - Metabolic syndrome, diabetes and cardiovascular disease
Evaluation:
5% Answer class questions
5% Q/A after student presentations
10% Student presentation 1
15% Midterm test
20% Student presentation 2
20% 1 page summary and critique
25% Final assessment
