Min Zhuo In the News

Jun 13, 2018

Could the Brain’s Frontal Lobe Be Involved in Chronic Pain?

May 25, 2018 Author: Heidi Singer

A University of Toronto scientist has discovered the brain’s frontal lobe is involved in pain transmission to the spine. If his findings in animals bear out in people, the discovery could lead to a new class of non-addictive painkillers.

For 20 years, Min Zhuo, a professor of Physiology in the Faculty of Medicine, has been intrigued by invisible pain; in particular, chronic pain with no obvious cause. He has long suspected that the standard way of viewing spinal pain – it must come from injury or tissue inflammation – and the usual understanding of how to treat it – block it from entering the spinal cord – wasn’t telling the whole story.

Dr. Min Zhuo

Now, Zhuo has demonstrated in mice and rats that some spinal pain actually begins in the brain’s frontal lobe, an area previously thought to be uninvolved. And he has shown how treating the pain in this area could be effective at preventing chronic pain. Zhuo published his results May 16 in the journal Nature Communications. Keep Reading….

More Exciting News

Dr. Zhuo has just published another important paper in  Nature Communications.   Two  former U of T Physiology post docs, Tao Chen and Shuang Qiu, are also listed on the paper.  Congratulations to all!

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