Department of Physiology

Xiao-Yan Wen PhD
Assistant Professor
Cardiovascular and Respiratory Platform
wen
Contact Info
T: (416) 847-1737
Website
Location
209 Victoria Street, LKSK, Room 519
Toronto, ON, M5B 1T8
Accepting
Graduates
Appointments
Primary: Department of Medicine
Research Interests
1. Genome wide gene trapping and mutagenesis in zebrafish 2. Large scale high throughput chemical genetic screening for in vivo drug discovery using zebrafish embryos 3. Functional genomics and disease modeling

Research/Teaching

Research Synopsis

Research Interests:

1. Genome wide gene trapping and mutagenesis in zebrafish
2. Large scale high throughput chemical genetic screening for in vivo drug discovery using zebrafish embryos
3. Functional genomics and disease modeling

Keywords: Zebrafish, disease modeling, high throughput, mutagenesis, gene trapping, chemical genetics, drug development.

METHODS USED

Cell and tissue culture: Brain slice, cardiomyocytes, endothelial cells, pancreas cells.

Procedures: Behavioural tests, gene expression analysis, immunohistochemistry, qRT-PCR, RT-PCR, western blot.

EQUIPMENT USED

Amplifier, analytical balances, benchtop centrifuge, blotting apparatus, confocal microscope, culture hood, culture incubators, digital microscope, dissecting microscope, electrometer, fluorescence microscope, microwave oven, plate reader.

PRESENT TRAINEES

Jennifer Tat
Wing Hui
David Spillane
Suzan El-Rass
Antonio Mauro
Filip Miscevic

Publications and Awards

View PubMed search of this faculty member's recent publications.

Recent Publications

http://www.ncbi.nlm.nih.gov/pubmed/26020268