Research Divisions: Experimental Therapeutics
Research Interests: Heart failure following a myocardial infarction is a major clinical problem. Cardiac dysfunction after myocardial infarction is due to the loss of the heart muscle cells. We have developed a technique to implant stem cells into damaged heart tissue to repair and regenerate heart tissue. The pre-clinical data demonstrates that implanted cells can improve heart function. Clinical research is underway.
Keywords: Myocardial Infarction, Heart Failure, Cardiac regeneration, Cardiac function, Cardiac function measurement, Stem Cells, Animal models, Tissue engineering, Molecular biology, Conductive biomaterial.
Stem cells have been isolated and implanted into damaged heart post heart attack. The transplanted cells survived in the heart tissue.
Procedures: Cell culture, Molecular biological procedures, Cardiac operation and animal model creation. Heart function analysis.
Daniel Ramnath (MSc. Candidate)
Mike Lee (PhD Candidate)
Zhi Cui (PhD Candidate)
Tina Binesh Marvasti (MD/PhD Candidate)
Stephanie Tobin (Post-doctoral fellow)
Azadeh Yeganeh (Post-doctoral fellow)